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Erik Kopping is a Ph.D. Candidate in the Graduate Memoranda in Molecular Study of flora and Microbiology working in the laboratory of Dr. Chris are friends Thanassi. Eriks treatise work highlights whence a microbial pathogen, Francisella tularensis, counteracts the shoals innate immune response to infection. F. Tularensis could certainly cause a severe, and most often terminal, pneumonia in men. Due to peculiar extreme contamination, several native land weaponized F. Tularensis, prompting fear that F. Tularensis could be used as a ability biothreat intermediary. Therefore, an increased understanding of F. Tularensis pathogenesis is pretty important to help develop an effective vaccine to combat this threat. Currently, Eriks research pitch into precisely how the F. Tularensis outer membrane pass protein TolC contributes to immune evasion during infection of macrophages. He is working to understand in any event TolC is going (i.E. Through virulence info secretion) in place to delay the macrophage programmed cell death responses during infection. This function of TolC is crucial considering that it allows on the bacterium to reside and replicate in the macrophage undetected without exposure to extracellular quantity defenses. The GSO Gala Travel Gift will help fund Eriks occupancy at the Gordon Research Conference on Microbial Toxins and Pathogenicity where he will contemporaneous a poster on the role of TolC in F. Tularensis pathogenesis. The conference will be attended by some of the apogee prominent researchers in the community of host-pathogen interactions and will be a strong opportunity to showcase the exciting research conducted at Stony Brook University.

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