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Erik Kopping is a Ph.D. Candidate in the Graduate Model in Molecular Morphology and Microbiology working in the laboratory of Dr. Mark Thanassi. Eriks talk work discusses whence a microbial pathogen, Francisella tularensis, counteracts the scrape innate immune response to infection. F. Tularensis may want to cause a severe, and most often deathly, pneumonia in biped. Due to peculiar extreme irritation, several countries around the world weaponized F. Tularensis, prompting fear that F. Tularensis could be used as a implied biothreat intermediary. Therefore, a bigger understanding of F. Tularensis pathogenesis is choleric to help develop an effective vaccine to combat this threat. Currently, Eriks research give how the F. Tularensis outer membrane watercourse protein TolC contributes to immune evasion during infection of macrophages. He is working to understand by means of TolC is working (i.E. Through virulence creador secretion) in place to delay the macrophage programmed cell death responses during infection. This function of TolC is crucial considering that it allows in your bacterium to reside and replicate in the macrophage undetected without exposure to extracellular coordinate defenses. The GSO Royal Travel Allowance will help fund Eriks companionship at the Gordon Research Conference on Microbial Toxins and Pathogenicity where he will gift idea a poster on the role of TolC in F. Tularensis pathogenesis. The conference will be attended by some of the most of prominent researchers in the domain of host-pathogen interactions and will be a opportunity to showcase the exciting research conducted at Stony Brook University.
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